Main Page
About Science
Faculty Deanship
Letter of Dean
Overview of Deanship
Vice Deans
Vice Dean
Letter of Vice-dean
Overview of Vice-deanship
Vice Dean for Graduate Studies
Letter of Vice Dean for Graduate Studies
Overview of Vice Dean of Postgraduate Studies
Research and Innovation Unit
Vice Dean for Girls Campus
Faculty Management
Letter of Managing Director-Boys Campus
Letter of Managing Director-Girls Campus
Overview of Management
Educational Affairs
Males Campus
Staff
Females Campus
Contact Us
Research
عربي
English
About
Admission
Academic
Research and Innovations
University Life
E-Services
Search
Faculty of Sciences
Document Details
Document Type
:
Article In Journal
Document Title
:
Synthesis, Characterization, and In Vitro Antibacterial Activities of Macromolecules Derived from Bis-Chalcone
Synthesis, Characterization, and In Vitro Antibacterial Activities of Macromolecules Derived from Bis-Chalcone
Document Language
:
English
Abstract
:
We investigated the antibacterial activity of some new macromolecules such as bis-pyrazoline, bis-pyrazole, bis-pyrimidines prepared from the reaction of bis-chalcone with thiosemicarbazide/phenyl hydrazine/guanidine hydrochloride/thiourea. All the macromolecules have been characterized by IR, 1H NMR, 13C NMR, mass and elemental analyses. The antibacterial activity of these compounds was first tested in vitro by the disc diffusion assay against two Gram-positive and two Gram-negative bacteria, and then the minimum inhibitory concentration was determined with the reference to standard drug chloramphenicol. The results showed that pyrazoline derivative showed better antibacterial activity on S. typhimurium and E. coli than the reference drug chloramphenicol.
ISSN
:
0022-152X
Journal Name
:
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume
:
49
Issue Number
:
6
Publishing Year
:
1433 AH
2012 AD
Article Type
:
Article
Added Date
:
Wednesday, July 12, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
A Asiri
Asiri, A
Researcher
S Khan
Khan, S
Researcher
Files
File Name
Type
Description
42080.pdf
pdf
Back To Researches Page