Document Details

Document Type : Article In Journal 
Document Title :
GINGIV AL CREVICULAR FLUID INTERLEUKIN-8 IN PREGNANT WOMEN: CORRELATION WITH PROGESTERONE LEVEL
GINGIV AL CREVICULAR FLUID INTERLEUKIN-8 IN PREGNANT WOMEN: CORRELATION WITH PROGESTERONE LEVEL
 
Document Language : English 
Abstract : The gingivitis associated with pregnancy has been attributed to increased concentrations of circulating estrogen and/or progesterone. However. the mechanism by which these hormones increase gingival inflammation is not known. IL-8 is a potent chemoattractant for PMNL, which constitute the first and most abundant cell population in early inflammatory lesions. This study was conducted on 30 pregnant females (lOin each trimester) and 10controls to assess their GCF IL-8 concentration and to find a relationship, if possible, with clinical periodontal variables in pregnancy. The concentration of GCF IL-8 has decreased throughout pregnancy in comparison to controls. GCF IL-8 concentrations revealed significant negative correlations with PBI, CLA, and serum progesterone level. No significant correlations were found as regards serum IL-8 level, denoting much more importance of the local host response to bacterial challenge.The decrease in GCF IL-8 level may be part of maternal immunosuppression associated with increased progesterone during pregnancy, and may modulate the development of localized intlammation. 
ISSN : 0 
Journal Name : Egyptian Dental Journal 
Volume : 46 
Issue Number : 2 
Publishing Year : 1420 AH
2000 AD 
Article Type : Article 
Added Date : Tuesday, October 19, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
غادة منصورMansour, Ghada ResearcherDoctorate 

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 27833.pdf pdf 

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