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Faculty of Dentistry
Document Details
Document Type
:
Article In Journal
Document Title
:
Expression of Apoptotic Signaling Protein p53 andCell Proliferation Associated Protein Ki-67 in Oral
Expression of Apoptotic Signaling Protein p53 andCell Proliferation Associated Protein Ki-67 in Oral
Document Language
:
English
Abstract
:
Oral Lichen Planus (OLP) is a chronic inflammatory oral mucosal disease that appears in be related lo a cell mediated-immune process. In OLP destruction of the basal cell layer as well as changes in cell proliferation, cell repair and cell death occur in the injured mucosal epithelium. Histologically OLP is characterized by hyperkeratosis. basal cell liquefaction and intense infiltration of lymphocytes at epithelial- connective tissue interface. It has been suggested that OLP may be a premalignant lesion since oral squamous cell carcinoma (OSCC) have been observed in few patients affected by OLP. The aim of this study was to examine the expression of apoptotic signaling protein p53 and the cell proliferation associated protein Ki- 67 in OLP and OSCC in order to evaluate possible transition of OLP to OSCC
ISSN
:
111
Journal Name
:
Ainshams Dental Journal
Volume
:
111
Issue Number
:
1
Publishing Year
:
1425 AH
2005 AD
Article Type
:
Article
Added Date
:
Friday, October 30, 2009
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سوزان سيف الله إبراهيم
ibrahim, , suzan seif
Investigator
Doctorate
هدير فؤاد الدسوقي
EL-DESSOUKY, hadier
Researcher
Master
Files
File Name
Type
Description
23646.pdf
pdf
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