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Document Details
Document Type
:
Article In Journal
Document Title
:
Hepatitis C Virus Infection in Pregnant Women and its Vertical Transmission in Jeddah, Saudi Arabia
عدوى الالتهاب الكبدي الفيروسي ج في الحوامل وانتقاله الرأسي بجدة بالمملكة العربية السعودية
Subject
:
Original Articles
Document Language
:
English
Abstract
:
The aim of this study was to evaluate the prevalence of Hepatitis C virus (HCV) infection among pregnant women and the possibility of its transmission through the vertical route and through breast-feeding. Blood samples were collected from 300 pregnant women at the perinatal period and at delivery from the cord blood of their newborns, and from other 300 randomly selected breast-fed infants. Serum transaminases, anti-HCV Ab and HCV-RNA by PCR for only those with positive anti- HCV Ab were investigated. Results revealed that 9 (3%) mothers were positive for anti-HCV Ab and 8 (2.7%) were positive for HCV-RNA (viral load was below 5,000 copies / ml). However, only 5 newborns of HCV-RNA positive mothers showed positive results in (1.6%) for anti- HCV Ab, while all of them were negative by HCV-RNA. Meanwhile, all of the breast-fed infants were negative for anti- HCV Ab. Thus, this study could not reveal HCV transmission from mother to infant during the period of observation, yet a vertical transmission of HCV Ab was noticed. It is felt that it is not necessary to advise against breast-feeding prevention by mothers with HCV infection as long as there is no nipple cracking or bleeding.
ISSN
:
1319-1004
Journal Name
:
Medical Science Journal
Volume
:
14
Issue Number
:
1
Publishing Year
:
1428 AH
2007 AD
Number Of Pages
:
8
Article Type
:
Article
Added Date
:
Sunday, October 11, 2009
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
عبدالله أحمد الغامدي
Abdullah A. Al-Ghamdi
Researcher
Files
File Name
Type
Description
22246.pdf
pdf
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